about hepatitis b virus pres1 antigen clinical applications（对乙型肝炎病毒pres1抗原的临床应用）.docVIP

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about hepatitis b virus pres1 antigen clinical applications（对乙型肝炎病毒pres1抗原的临床应用）.doc

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about hepatitis b virus pres1 antigen clinical applications（对乙型肝炎病毒pres1抗原的临床应用）

About hepatitis B virus PreS1 antigen clinical applications [Abstract] Objective To investigate the hepatitis B virus (HBV pre-S1 antigen (Pre-S1 and hepatitis B virus DNA (HBV-DNA and hepatitis B e antigen (HBeAg, hepatitis B diagnosis, efficacy assessment scientific basis. Methods 1120 cases of clinical specimens were used quantitative PCR to detect HBV-DNA load using enzyme-linked immunosorbent assay (ELISA detection of HBeAg; using enzyme-linked immunosorbent assay (ELISA detection of pre-S1 antigen results of 569 cases of HBV-DNA PCR positive specimens, 448 cases of pre-S1 antigen positive, HBeAg-positive 252 cases, two test results between the existence of significant differences (P lt;0.05. Conclusions Serum Pre-S1 antigen, HBeAg and HBV replication is closely related to as indicators reflect HBV replication, before S1 antigen is superior to HBeAg, Pre-S1 antigen of hepatitis B epidemiological investigation and has important clinical value in the clinical diagnosis and therapeutic aspects. Words] Pre-S1 antigen of hepatitis B e antigen of hepatitis B virus Hepatitis B virus (HBV infection is a global health concern, the most common cause of chronic liver disease worldwide lead our country for the high incidence of about 10% of the population of HBV carriers. Study found, HBV pre-S1 antigen (PreSl-Ag detection of hepatitis B early diagnosis, illness and drug treatment and prognosis has very important significance, PreS1-Ag is following the “hepatitis B two pairs of semi test new markers of HBV infection. antigen of hepatitis B hepatitis virus pre-S1, pre-S2 antigen and HBeAg three together constitute the hepatitis B hepatitis virus (HBV shell protein [1-2] HBV-DNA PCR detection of hepatitis B virus replication gold standard, due to the experiment itself on the experimental conditions the higher other factors constraints, usually clinical and more as a basis reflecting viral replication to detect serum markers of hepatitis B HBeAg but currently more e