analysis of lung cancer tumor markers progress（肺癌肿瘤标记物的分析进展）.docVIP

Analysis of lung cancer tumor markers progress [Abstract] In recent years, TM is widely used in detection of lung cancer diagnosis and treatment, recurrence, the prognosis. This paper reviews recent studies of lung cancer markers of the progress and research prospects. [Keywords:] lung cancer tumor marker research Tumor markers (tumormarker, TM) is a cancer cell in the occurrence, development, invasion and metastasis of the activity of secreted substances present in the host tissue and body fluids. In recent years, as molecular biology, immunology and biochemistry the rapid development of other related disciplines, TM testing is widely used in cancer diagnosis and for treatment, recurrence, the prognosis. tumor markers (tumormarker, TM) research is very active. tumor markers with high specificity, high sensitivity, convenient, easy to obtain specimens and trauma, etc. [1], tumor markers, early diagnosis of lung cancer screening has been the focus of the study. A lung tumor marker currently used 1.1 embryonic antigen tumor markers Carcinoembryonic antigen (CEA) is a lung adenocarcinoma (Ad) marker The study found that Ad cells can directly produce CEA, so the positive rate was higher; in small cell lung cancer (SCLC) and lung squamous cell carcinoma (Sq) in some increased [2]. Therefore, diagnosis and treatment of lung cancer, CEA is currently the most commonly used markers, the increased number of cancer cells is directly related to the degree of its sensitivitygt; = 50% [3]. 1.2 carbohydrate markers CA153 is an important breast cancer TM, exist in a variety of Ad inside. It has been reported in the Ad in the lung was higher than CEA [4], can be used to monitor lung TM. 1.3 enzyme markers Normal neuron-specific enolase (NSE) specifically located in neurons and neuroendocrine cells, such as cells derived from neural ectoderm, an amine precursor uptake and decarboxylation of the cell lines (referred to as APUD cells) [ 5]. SCLC