a new natural lactone from dimocarpus longan lour. seeds一个新的自然内酯从花芽龙眼不悦之色。.pdfVIP

Molecules 2012, 17, 9421-9425; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article A New Natural Lactone from Dimocarpus longan Lour. Seeds Gongming Zheng 1,2,*, Xiaoyi Wei 2, Liangxiong Xu 2, Zhongjun Li 1, Gangyong Liu 1 and 1 Xiance Zhang 1 Guangdong Food and Drug Vocational College, Guangzhou, Guangdong 510520, China; E-Mails: lizj@ (Z.L.); liugy@ (G.L.); zhangxc@ (X.Z.) 2 South China Botanical Garden, the Chinese Academy of Sciences, Guangzhou, Guangdong 510650, China; E-Mails: weixiaoy@ (X.W.); xlx048@ (L.X.) * Author to whom correspondence should be addressed; E-Mail: zhenggm@; Tel.: +86-020-2885-4943; Fax: +86-020-3721-6531. Received: 25 June 2012; in revised form: 18 July 2012 / Accepted: 1 August 2012 / Published: 6 August 2012 Abstract: A new natural product named longanlactone was isolated from Dimocarpus longan Lour. seeds. Its structure was determined as 3-(2-acetyl-1H-pyrrol-1-yl)-5-(prop-2-yn-1- yl)dihydrofuran-2(3H)-one by spectroscopic methods and HRESIMS. Keywords: Dimocarpus longan Lour.; longan seed; constituents; lactone 1. Introduction Longan [Dimocarpus longan Lour. (syn. Euphoria longana Lam.)] is an evergreen tree of the Sapindaceae family, which is widely cultivated in Southern China, India, and Southeast Asia [1]. Longan fruit is one of the most favoured tropical fruits in China [2]. Longan seeds have long been used as a folk medicine in China for treatment of acariasis, hernia, wound hemorrhages, eczema and s