a new prenylated flavanone from derris trifoliata lour.一个新的prenylated黄烷酮从鱼藤酮trifoliata不悦之色。.pdfVIP

Molecules 2012, 17, 657-663; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article A New Prenylated Flavanone from Derris trifoliata Lour. Cheng Jiang 1,†, Shengzi Liu 1,†, Weihong He 2, Xiongming Luo 2, Si Zhang 2, Zhihui Xiao 2, Ximin Qiu 1,* and Hao Yin 2,* 1 Department of Pharmacy, Medical College, Hunan Normal University, Changsha 410006, China; E-Mails: dangdangli@ (C.J.); shengziliu@163.com (S.L.) 2 Key Laboratory of Marine Bio-resourses Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China; E-Mails: whhe@ (W.H.); luoxm163@ (X.L.); zhsimd@ (S.Z.), xzh_77@ (Z.X.) † These authors contributed equally to this work. * Authors to whom correspondence should be addressed; E-Mails: qiuximin@ (X.Q.); yinhao@ (H.Y.); Tel.: +86-20-8902-3105 (X.Q.); Fax: +86-136-6730-2556 (X.Q.); Tel./Fax: +86-20-8902-3105 (H.Y.). Received: 30 October 2011; in revised form: 26 December 2011 / Accepted: 27 December 2011 / Published: 11 January 2012 Abstract: A new flavanone, 4′,5,7-trihydroxy-6,8-di-(2-hydroxy-3-methylbut-3-enyl)- flavanone, was isolated from the aerial parts of Derris trifoliate , together with eleven known compounds: rotenone, tephrosin, 12a-hydroxyrotenone, deguelin, 6a,12a-dehydro- rotenone, dehydrodeguelin, 7a-O-methyldeguelol, 7a-O-methylelliptonol, 5,7,3,4-tetra- hydroxy-6,8-diprenylisoflavone, daidzein and 4-hydroxy-7-methoxyflavanone.