a rhodanine agent active against non-replicating intracellular mycobacterium avium subspecies paratuberculosis绕丹宁代理积极反对non-replicating细胞内鸟结核分枝杆菌亚种副结核.pdfVIP

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a rhodanine agent active against non-replicating intracellular mycobacterium avium subspecies paratuberculosis绕丹宁代理积极反对non-replicating细胞内鸟结核分枝杆菌亚种副结核.pdf

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a rhodanine agent active against non-replicating intracellular mycobacterium avium subspecies paratuberculosis绕丹宁代理积极反对non-replicating细胞内鸟结核分枝杆菌亚种副结核

Gut Pathogens BioMed Central Research Open Access A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis 1 1 1 2 Tim J Bull* , Richard Linedale , Jason Hinds and John Hermon-Taylor Address: 1Department of Cellular and Molecular Medicine, St Georges University, Cranmer Terrace, London, SW17 0RE, UK and 2Division of Nutritional Sciences, Franklin-Wilkins Building, Kings College London, 150 Stamford Street, London SE1 9NH, UK Email: Tim J Bull* - tim.bull@sgul.ac.uk; Richard Linedale - rlinedal@sgul.ac.uk; Jason Hinds - jhinds@sgul.ac.uk; John Hermon- Taylor - jhermon@kcl.ac.uk * Corresponding author Published: 23 December 2009 Received: 1 December 2009 Accepted: 23 December 2009 Gut Pathogens 2009, 1:25 doi:10.1186/1757-4749-1-25 This article is available from: /content/1/1/25 © 2009 Bull et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Antibiotic therapy targeting chronic mycobacterial disease is often ineffective due to problems with the emergence of drug resistance and non-replicating persistent intracellular antibiotic resistant phenotypes. Strategies which include agents able t