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a survey of visualization tools for biological network analysis生物网络可视化工具的调查分析
BioData Mining BioMed Central
Review Open Access
A survey of visualization tools for biological network analysis
Georgios A Pavlopoulos*, Anna-Lynn Wegener and Reinhard Schneider
Address: Structural and Computational Biology Unit, EMBL, Meyerhofstrasse 1, Heidelberg, Germany
Email: Georgios A Pavlopoulos* - pavlopou@embl.de; Anna-Lynn Wegener - wegener@embl.de; Reinhard Schneider - rschneid@embl.de
* Corresponding author
Published: 28 November 2008 Received: 25 June 2008
Accepted: 28 November 2008
BioData Mining 2008, 1:12 doi:10.1186/1756-0381-1-12
This article is available from: /content/1/1/12
© 2008 Pavlopoulos et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The analysis and interpretation of relationships between biological molecules, networks and
concepts is becoming a major bottleneck in systems biology. Very often the pure amount of data
and their heterogeneity provides a challenge for the visualization of the data. There are a wide
variety of graph representations available, which most often map the data on 2D graphs to visualize
biological interactions. These methods are applicable to a wide range of problems, nevertheless
many of them reach a limit in terms of user friendliness when thousands of
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