hyperuricemia and gout integrative analysis of progress（高尿酸血和痛风综合分析的进展）.docVIP

Hyperuricemia and gout Integrative analysis of progress Author: Wang Yan Gang, Yan victory, Miao Zhimin [Keywords] high uric acid Hyperuricemia and gout, not only can cause joint swelling, and can induce and aggravate dyslipidemia, diabetes and cardiovascular disease, increased cardiovascular and cerebrovascular diseases, metabolic syndrome and kidney disease patient mortality Therefore, the two has become a serious threat to human health, common diseases and frequently-occurring to take Integrative treatment of traditional Chinese medicine and Western advanced medical technology can complement each other, to tackling the purpose of hyperuricemia and gout. therefore more and more attention. now hyperuricemia and gout in Integrative Medicine Research progress are summarized below. 1 hyperuricemia and gout hazards and the need for prevention and treatment of The hyperuricemia case the scope of the metabolic syndrome. Recent years, with the improvement of people’s living standards, the metabolic syndrome, in particular, the incidence of hyperuricemia increased year by year. Hyperuricemia is the gout important biochemical basis, and the early stages of gout Although there is no clinical symptoms of this stage, but the urate causing tissue damage can not be ignored. Deposition of uric acid can cause gout arthritis in the joints, leading to dysfunction and joint deformities, gouty nephropathy can cause deposition in the kidney, leading to kidney failure. Moreover, hyperuricemia can also cause damage to other organs, tissues. Studies have shown that gout patients insulin sensitivity decreased, insulin the early secretory function disorders, simple high uric acid patient plasma plasminogen activator inhibitor (PAI1 endothelin (ET) was significantly higher, and prompted hyperuricemia can cause vascular endothelial cell injury, and aggravated with glucose and lipid metabolism disorders. CARNETHON [1] conducted a large sample of 10-year prospective study showe