hyperuricemia in patients with brachial artery diameter changes in the 35 cases of the（高尿酸血患者的肱动脉直径变化的35例）.docVIP

Hyperuricemia in patients with brachial artery diameter changes in the 35 cases of the Author: Lu Yan, Xu Shan, Su-Hua Zhang, Li Qian [Keywords:] hyperuricemia; vascular endothelial; vasodilation 1 Clinical data 200 405/200 511 hyperuricemia in patients 35 (28 male, 7 females, age 40 + -17 (35 to 68 years old, choose uric acid to normal in 35 patients as a control group, age 35 + -19 (35 to 65 years old. Fasting 12 h venous blood, the serum was separated by centrifugation, urease measured serum uric acid concentration: Malegt; = 420 mmol / L, womengt; = 390 mmol / L hyperuricemia Gelermajer reference [1] introduced the method using high resolution ultrasound detection of brachial artery reactive hyperemia (flow-mediated endothelium-dependent vasodilation and nitroglycerin (endothelium-dependent vasodilation relaxation response, 2 ~ 5 cm of the brachial artery to elbow on target for take its longitudinal section, find the lumen of the interface in the distance between the vascular end-diastolic measurements before and after the brachial artery intima, every three cardiac cycles were measured and averaged tested before resting for 10 min, in the determination of the basis of the value of (D0 reactive hyperemia test: blood pressure cuff set target artery distal inflatable pressurized to 300 mmHg for 4 min deflated deflated 60 ~ 90 s Niece brachial artery diameter (D1, rest for 10 min after the tongue glycerol 0.5 mg sublingual under 5 min, and then measuring the brachial artery diameter (D2 ultrasound probe is always in a fixed position throughout the testing process, the vessel diameter measurements were taken the same position every time. flow-mediated endothelium-dependent vasodilation function, FMD (%) = (D1-D0 / D0 ?100, nitroglycerin-mediated endothelium-dependent vasodilation NID (% = (D2-D0 / D0 ?100. RESULTS brachial artery diameter at baseline and brachial artery diameter changes in the two groups after sublingual nitroglycerin no difference (Pgt;