experimental cerebral hemorrhage in the acute phase plasma and brain tissue interleukin-6 content（实验性脑出血急性期血浆和脑组织中白细胞介素- 6的内容）.docVIP

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experimental cerebral hemorrhage in the acute phase plasma and brain tissue interleukin-6 content（实验性脑出血急性期血浆和脑组织中白细胞介素- 6的内容）.doc

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experimental cerebral hemorrhage in the acute phase plasma and brain tissue interleukin-6 content（实验性脑出血急性期血浆和脑组织中白细胞介素- 6的内容）

Experimental cerebral hemorrhage in the acute phase plasma and brain tissue interleukin-6 content Author: GAVIN Lvyun Li concocted a Lu Wei [Keywords] cerebral hemorrhage Keywords: cerebral hemorrhage, acute; interleukin-6; rats; plasma; brain tissue Abstract: Objective To investigate the interleukin-6 (IL-6 content in experimental cerebral hemorrhage in the brain tissue and plasma, and to clarify its role in the process of cerebral hemorrhage. Methods 80 SD rats, body weight 250 ~ 300g randomly divided into 4 groups: control group, a small amount of bleeding in the amount of bleeding group, heavy bleeding group and each group was divided into five groups, each group of four. Nath Law to establish the model of cerebral hemorrhage. determined by radioimmunoassay content of IL-6 in plasma and brain tissue results cerebral hemorrhage, brain tissue and plasma IL-6 levels significantly increased (P lt;0.05), the trend of increase with the amount of cerebral hemorrhage, bleeding at different times after IL -6 significant difference (P lt;0.05, to 48h the highest (P lt;0.01. Conclusion IL-6 increased is brain damage to white blood cells and the central nervous system bleeding injury immune response changes, monitoring the changes of IL-6. after cerebral hemorrhage nerve changes and discriminant prognosis of positive significance. Keywords: cerebral hemorrhage, acute; IL-6; rat; plasma; perihemotoma Abstract: AIM To investigate IL-6concentration change in brain tissue and plasma after acute cerebral hemorrhage in rats and reveal the action of the IL-6during the brain bleed ┐ ing.METHODS Eighty SD rats weighting250 ~ 300g were divided into four groups.Each group was further divided into five subgroups.The model of acute cerebral hemorrhage was established by Nath method.The concentrations of IL-6in plasma and brain tissues were measured with radioimmu-noassay.RESULTS The levels of LI-6in plasma and brain tissue in experimental groups remarkably increased (P l