脊柱转移瘤经椎体成形术疗效的MRI评价.pdfVIP

脊柱转移瘤经皮椎体成形术疗效的MRI 评价 中文摘要 脊柱转移瘤经皮椎体成形术疗效的MRI 评价 中文摘要 目的: 判断MRI 检查结果能否为临床脊柱转移瘤患者经皮椎体成形术（PVP ） 术后疗效提供可靠的客观评价。 方法: 本文回顾性分析36 例患者共75 节椎体转移瘤采用单纯PVP 治疗的临床 及医学影像学检查资料。术前及术后进行视觉模拟疼痛评分（VAS ）。根据MRI 检查 显示分为三组：病灶完全消失并持续 12 周为完全缓解(A 组) ；病灶出现骨化或肿瘤 体积缩小,无新转移灶出现并连续保持 12 周为部分缓解（B 组）；通过测量肿瘤体积 反映病灶扩大,表示无效（C 组）。然后比较3 组术前、术后12 周疼痛缓解程度。 结果: 3 组间术前VAS 差异无统计学意义（P0.05 ），术后C 组疼痛缓解不明显， A 组比B 组疼痛缓解程度大，疼痛缓解程度差异有统计学意义（P0.05 ）。表明MRI 客观检查结果与临床主观评价一致。 结论: PVP 是治疗脊柱转移瘤的有效方法，MRI 检查能为临床脊柱转移瘤患者 PVP 术后疗效提供可靠的客观评价。 【关键词】:脊柱转移瘤；磁共振成像；经皮椎体成形术 作 者：易 飞 指导教师：吴春根 I 英文摘要 脊柱转移瘤经皮椎体成形术疗效的MRI 评价 MRI EVALUATION OF PERCUTANEOUS VERTEBROPLASTY FOR SPINAL METASTASES Abstract Objective: The main purpose of this article is to determine whether MRI findings can provide reliable and objective evaluation of percutaneous vertebroplasty (PVP) in treating spinal metastases . Methods: PVP procedures were carried out in a total of 36 consecutive patients with 75 vertebral metastases ．The clinical data and the imaging materials were retrospective analyzed ．Visual analog scale (VAS) was determined before and after the treatment. According to MRI findings on sagittal scans ，the patients were divided into three groups. Group A(complete remission group): the lesions completely disappeared for 12 weeks. Group B(partial remission group):the lesions developed ossification or the tumor’s volume decreased, no new metastases appeared,and the condition maintained for 12 consec