糖尿病大鼠侧脑室脉络丛及脑小血管基底膜的观察及脑小血管α-SMA及CD31表达的研究.pdfVIP

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糖尿病大鼠侧脑室脉络丛及脑小血管基底膜的观察及脑小血管α-SMA及CD31表达的研究.pdf

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糖尿病大鼠侧脑室脉络丛及脑小血管基底膜的观察及脑小血管α-SMA及CD31表达的研究

目录中文摘要……………………………………………………………………1 英文摘要……………………………………………………………………5 研究论文糖尿病大鼠侧脑室脉络丛及脑小血管基底膜的观察和脑小血管a．SMA及CD3l表达的研究弓I言········································…·········……····················11引舌一””“一“””””一“”一””“““一…“”一“”……一”“””“一”“‘11 第一部分糖尿病大鼠侧脑室脉络丛及脑小血管基底膜的观察前言······…···…······……··…·············……···…·········…······…12日IJ吾“””““”“““”一””一“…”一”“一“““”“一一”一“”””“”““‘12 材料与方法……………………………………………………………12 结果··············································································17 附l羽··································…································…······19 讨论············································…····························…23 ，J、结··一·一·········”··”·一···…····一·“····一·一······……····一”·········25 参考文献………………………………………………………………26 第二部分糖尿病大鼠脑小血管Q．SMA和CD31表达的研究前言···…·…··…······…······……···-··………·········……·……··…29日lJ吾”一”“…一””””“”””””…”””“””“一””一”…“”……””。29 材料与方法……………………………………………………………29 结果·························…·····…··········································34 附图················…···························································36 附表··……·························…··································-·······39 讨论··············································································40 硝、结·······…·······················…··························…···一········41 参考文献………………………………………………………………42 结论·············…············…-········································…···-·····45 综述代谢综合征与脑白质疏松症的相关研究…………………………46 致谢····················································································57 个人简历……………………………………………………………………58 中文摘要糖尿病大鼠侧脑室脉络丛及脑小血管基底膜的观察和脑小血管仅．SMA及CD31表达的研究摘要随着人口老龄化和人们生活方式的改变，糖尿病患者生存期明显延长。随之而来的慢性并发症越来越多见，其中关于自主神经及周围神经病变已有很多研究，糖尿病同样也会引起中枢神经系统损伤。但因缺乏特征性的早期诊断工具，故对糖尿病脑病的研究较少。糖尿病脑病的特点是神经