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浅析干扰素的不良反应(Analysis of adverse reactions of interferon)
浅析干扰素的不良反应(Analysis of adverse reactions of interferon)
Analysis of adverse reactions of interferon
Date: 07, 10
Abstract: This article reports some adverse reactions in interferon application, in order to remind clinicians to pay attention to the use of drugs and ensure the safe use of drugs.
Interferon; adverse reactions; antiviral
Interferon has many functions, such as anti-virus, anti-tumor, inhibiting cell proliferation and improving cellular immune function. It has been widely used in the treatment of viral diseases as viral diseases and tumor effective biological drugs. But some patients in the application process, in addition to the common adverse reactions: fever, chills, muscle pain, headache, fatigue, anorexia, nausea, there may also be some rare and serious adverse reactions, clinical should be paid enough attention to.
1 blood sugar [1]
The patient was admitted to the hospital due to chronic hepatitis B. He had no history of diabetes, kidney disease, heart disease, thyroid disease, psychiatric history, and a history of drug and food allergy. His father had a history of diabetes. At admission, fasting blood glucose, 4.6mmol/L, postprandial blood glucose, 7.2mmol/L, B ultrasound Abstract: diffuse liver injury. Give interferon (Li Ke Neng) 3 million U intramuscular injection, 1 times a day, 1 months later changed to the next 1 times, treatment at the end of sixth months of thirst, emaciation, fasting fasting blood glucose summary: 16.8mmol/L, normal liver function. Interferon was discontinued, and regular insulin, 10u, 6U and 8U were given subcutaneously before three meals a day. 1 weeks later, fasting blood glucose Abstract: 6.7mmol/L, postprandial blood glucose summary: 7.8mmol/L, but insulin can not be reduced, otherwise there will be abnormal blood sugar. The patient had no history of drug use, so the possibility was due to elevated blood sugar caused by interferon.
2 acute aplastic anemia [2]
Patients, male, 61 years old, lack of strength, chest tight
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