原创力文档a day in the life of microcystis aeruginosa strain pcc 7806 as revealed by a transcriptomic analysis生命中的一天微胞藻属的绿脓杆菌菌株pcc 7806透露了转录组分析.pdfVIP
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a day in the life of microcystis aeruginosa strain pcc 7806 as revealed by a transcriptomic analysis生命中的一天微胞藻属的绿脓杆菌菌株pcc 7806透露了转录组分析
A Day in the Life of Microcystis aeruginosa Strain PCC
7806 as Revealed by a Transcriptomic Analysis
´ 1. 1,2. 1,3 1,4
Cecile Straub , Philippe Quillardet , Julia Vergalli , Nicole Tandeau de Marsac , Jean-Franc¸ois
Humbert1,5*
´ ´ ´ ´ ´
1 Institut Pasteur, Collection des Cyanobacteries, Paris, France, 2 Institut Pasteur, Unite de Dynamique du Genome, Paris, France, 3 Institut Mediterraneen d’Ecologie et de
´ ´ ´ ´ ´ ´ ´ ´ ˆ
Paleoecologie, UMR-CNRS 6116, Ecologie des Eaux Continentales Mediterraneennes, C31, Universite Paul Cezanne, Faculte de St-Jerome, Marseille, France, 4 Laboratoire
´ ´
de Chimie Bacterienne, CNRS-UPR9043, Universite d’Aix-Marseille, Marseille, France, 5 INRA, UMR BIOEMCO, Site de l’ENS, Paris, France
Abstract
The cyanobacterium, Microcystis aeruginosa, is able to proliferate in a wide range of freshwater ecosystems and to produce
many secondary metabolites that are a threat to human and animal health. The dynamic of this production and more
globally the metabolism of this species is still poorly known. A DNA microarray based on the genome of M. aeruginosa PCC
7806 was constructed and used to study the dynamics of gene expression in this cyanobacterium during the light/dark
cycle, because light is a critical factor for this species, like for other photosynthetic microorganisms. This first application of
transcriptomics to a Microcystis species has revealed that more than 25% of
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