rapid recovery of fat mass in small for gestational age preterm infants after term快速复苏的脂肪量小胎龄后早产儿.pdfVIP

Rapid Recovery of Fat Mass in Small for Gestational Age Preterm Infants after Term 1 `1 1 1 1 1 Paola Roggero *, Maria L. Giannı , Nadia Liotto , Francesca Taroni , Anna Orsi , Orsola Amato , Laura 1 1 1,2 1 Morlacchi , Pasqua Piemontese , Massimo Agosti , Fabio Mosca 1 Neonatal Intensive Care Unit (NICU), Department of Mother and Infant Science, Fondazione IRCCS ‘‘Ca’ Granda’’ Ospedale Maggiore Policlinico, University of Milan, Milan, Italy, 2 Maternal and Child Health Department, Del Ponte Hospital, A.O. Di Circolo Fondazione Macchi, Varese, Italy Abstract Background: Preterm small for gestational age (SGA) infants may be at risk for increased adiposity, especially when experiencing rapid postnatal weight gain. Data on the dynamic features of body weight and fat mass (FM) gain that occurs early in life is scarce. We investigated the postnatal weight and FM gain during the first five months after term in a cohort of preterm infants. Methodology/Principal Findings: Changes in growth parameters and FM were prospectively monitored in 195 infants with birth weight #1500 g. The infants were categorized as born adequate for gestational age (AGA) without growth retardation at term (GR 2), born AGA with growth retardation at term (GR+), born SGA. Weight and FM were assessed by an air displacement plethysmography system. At five months, weight z-score was comparable between the AGA (GR+) and the AGA (GR 2), whereas the SGA showed a significantly lower weight.The mean weight (g) differences (95% CI) between SGA and AGA (GR 2) and between SGA and AGA (GR+) infants at 5 months were 2613 ( 21215; 212) a