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Rapid Species Diagnosis for Invasive Candidiasis Using Mass Spectrometry Carine Marinach-Patrice1,2, Arnaud Fekkar 1,2,3, Ralitsa Atanasova1,2, Johanna Gomes1,2, Laura 3 1,2,4 3 1,2,3 1,2,5 Djamdjian , Jean-Yves Brossas , Isabelle Meyer , Pierre Buffet , Georges Snounou , Annick Datry1,2,3, Christophe Hennequin1,2,6, Jean-Louis Golmard7., Dominique Mazier1,2,3.* ´ ´ ˆ ` 1 INSERM, U945, Paris, France, 2 Universite Pierre et Marie Curie-Paris6, UMR S945, Paris, France, 3 AP-HP, Groupe hospitalier Pitie-Salpetriere, Service Parasitologie- ´ ´ ˆ ` Mycologie, Paris, France, 4 Centre d’investigation Biomedical, Groupe hospitalier Pitie-Salpetriere, Paris, France, 5 Laboratory of Molecular and Cellular Parasitology, ˆ Department of Microbiology, Faculty of Medicine, National University of Singapore, Singapore, Singapore, 6 AP-HP, Hopital St Antoine, Service Parasitologie-Mycologie, ´ ´ Paris, France, 7 Universite Pierre et Marie Curie-Paris6, ER4/EA 3974, Modelisation en Recherche Clinique, Paris, France Abstract Background: Matrix-assisted laser desorption ionisation time of flight mass spectrometry (MALDI TOF-MS) allows the identification of most bacteria and an increasing number of fungi. The potential for the highest clinical benefit of such me