rational prescribing in primary care (rapp) a cluster randomized trial of a tailored interventionrational处方在初级保健(rapp)的集群随机试验的干预.pdfVIP

PLoS MEDICINE Rational Prescribing in Primary Care (RaPP): A Cluster Randomized Trial of a Tailored Intervention 1* 1 ˚ 1 2 1 1 Atle Fretheim , Andrew D. Oxman , Kari Havelsrud , Shaun Treweek , Doris T. Kristoffersen , Arild Bjøørndal 1 Norwegian Knowledge Centre for Health Services, Oslo, Norway, 2 Tayside Centre for General Practice, University of Dundee, Dundee, United Kingdom Funding: The study was funded by A B S T R A C T the Norwegian Ministry of Health, the Norwegian Directorate for Background Health and Social Affairs, and the Norwegian Knowledge Centre for Health Services. The funding A gap exists between evidence and practice regarding the management of cardiovascular agencies had no influence on the risk factors. This gap could be narrowed if systematically developed clinical practice guidelines design or conduct of the study. were effectively implemented in clinical practice. We evaluated the effects of a tailored Competing Interests: All the intervention to support the implementation of systematically developed guidelines for the use authors are, or have been, employed of antihypertensive and cholesterol-lowering drugs for the primary prevention of cardiovas- by the Norwegian government, cular disease. which has a substantial interest in improving professional practice in Norway and in containing the costs of health care. The clinical practice Methods and Findings guidelines and the study design have not been endorsed by the We conducted a cluster-randomized trial