reconstruction and comparison of the metabolic potential of cyanobacteria cyanothece sp. atcc 51142 and synechocystis sp. pcc 6803重建和蓝藻蓝杆菌的代谢潜力比较sp。写明atcc 51142集胞藻属pcc 6803 sp.pdfVIP

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reconstruction and comparison of the metabolic potential of cyanobacteria cyanothece sp. atcc 51142 and synechocystis sp. pcc 6803重建和蓝藻蓝杆菌的代谢潜力比较sp。写明atcc 51142集胞藻属pcc 6803 sp.pdf

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reconstruction and comparison of the metabolic potential of cyanobacteria cyanothece sp. atcc 51142 and synechocystis sp. pcc 6803重建和蓝藻蓝杆菌的代谢潜力比较sp。写明atcc 51142集胞藻属pcc 6803 sp

Reconstruction and Comparison of the Metabolic Potential of Cyanobacteria Cyanothece sp. ATCC 51142 and Synechocystis sp. PCC 6803 1 1 2 1 2,3 Rajib Saha , Alex T. Verseput , Bertram M. Berla , Thomas J. Mueller , Himadri B. Pakrasi , Costas D. Maranas1* 1 Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania, United States of America, 2 Department of Energy, Environmental, and Chemical Engineering, Washington University, St. Louis, Missouri, United States of America, 3 Department of Biology, Washington University, St. Louis, Missouri, United States of America Abstract Cyanobacteria are an important group of photoautotrophic organisms that can synthesize valuable bio-products by harnessing solar energy. They are endowed with high photosynthetic efficiencies and diverse metabolic capabilities that confer the ability to convert solar energy into a variety of biofuels and their precursors. However, less well studied are the similarities and differences in metabolism of different species of cyanobacteria as they pertain to their suitability as microbial production chassis. Here we assemble, update and compare genome-scale models (iCyt773 and iSyn731) for two phylogenetically related cyanobacterial species, namely Cyanothece sp. ATCC 51142 and Synechocystis sp. PCC 6803. All reactions are elementally and charge balanced and localized into four different intracellular compartments (i.e., periplasm, cytosol, carboxysome and thylakoid lumen) and biomass descriptions are derived based on experimental measurements. Newly added reactions absent in earlier models (266 and 322, respectively