原创力文档results of antiretroviral treatment interruption and intensification in advanced multi-drug resistant hiv infection from the optima trial抗逆转录病毒治疗的中断和加强在先进耐多药hiv感染的最适条件试验.pdfVIP
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results of antiretroviral treatment interruption and intensification in advanced multi-drug resistant hiv infection from the optima trial抗逆转录病毒治疗的中断和加强在先进耐多药hiv感染的最适条件试验
Results of Antiretroviral Treatment Interruption and
Intensification in Advanced Multi-Drug Resistant HIV
Infection from the OPTIMA Trial
1,2 3,4 5,6 7 8
Mark Holodniy , Sheldon T. Brown , D. William Cameron *, Tassos C. Kyriakides , Brian Angus ,
9 6 1,2 6 9 9
Abdel Babiker , Joel Singer , Douglas K. Owens , Aslam Anis , Ruth Goodall , Fleur Hudson ,
6 7 6 10¤ 9
Mirek Piaseczny , John Russo , Martin Schechter , Lawrence Deyton , Janet Darbyshire , for the
OPTIMA Team
1VA Palo Alto Health Care System, Palo Alto, California, United States of America, 2 Department of Medicine, Stanford University, Stanford, California, United States of
America, 3 James J. Peters VA Medical Center, Bronx, New York, United States of America, 4 Department of Medicine, Mt. Sinai School of Medicine, New York, New York,
United States of America, 5 University of Ottawa at The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, 6 Canadian HIV Trials Network, St Paul’s Hospital,
Vancouver, British Columbia, Canada, 7 VA Cooperative Studies Program Coordinating Center, West Haven, Connecticut, United States of America, 8 Nuffield Department
of Medicine, The John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom, 9 MRC Clinical Trials Unit, London, United Kingdom, 10 Department of Veterans
Affairs, Office of Public Health and Environmental Hazards, Washington, D.C., United States of America
Abstract
Background: Gu
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