season of birth and dopamine receptor gene associations with impulsivity, sensation seeking and reproductive behaviors出生的季节和多巴胺受体基因协会与冲动,感觉寻求和生殖行为.pdfVIP

Season of Birth and Dopamine Receptor Gene Associations with Impulsivity, Sensation Seeking and Reproductive Behaviors 1,2,3,4 5 6,7 2,3,4 2,3 Dan T. A. Eisenberg *, Benjamin Campbell , James MacKillop , J. Koji Lum , David S. Wilson 1 Department of Anthropology, Northwestern University, Evanston, Illinois, United States of America, 2 Department of Anthropology, State University of New York at Binghamton, Binghamton, New York, United States of America, 3 Department of Biology, State University of New York at Binghamton, Binghamton, New York, United States of America, 4 Laboratory of Evolutionary Anthropology and Health, State University of New York at Binghamton, Binghamton, New York, United States of America, 5 Department of Anthropology, University of Wisconsin Milwaukee, Milwaukee, Wisconsin, United States of America, 6 Department of Psychology, State University of New York at Binghamton, Binghamton, New York, United States of America, 7 Center for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, United States of America Background. Season of birth (SOB) has been associated with many physiological and psychological traits including novelty seeking and sensation seeking. Similar traits have been associated with genetic polymorphisms in the dopamine system. SOB and dopamine receptor genetic polymorphisms may independently and interactively influence similar behaviors through their common effects on the dopaminergic system. Methodology/Principal Findings. Based on a sample of 195 subjects, we examined whether SOB was associated with impulsivity, sensation seeking and reproductive behaviors. Additionally we examined potential interactions of dopamine receptor genes with SOB for the same set of traits. Phenotypes