setting research priorities to reduce global mortality from childhood diarrhoea by 2015设置研究优先级到2015年减少全球儿童腹泻死亡率.pdfVIP
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setting research priorities to reduce global mortality from childhood diarrhoea by 2015设置研究优先级到2015年减少全球儿童腹泻死亡率
Guidelines and Guidance
Setting Research Priorities To Reduce Global
Mortality from Childhood Diarrhoea by 2015
Olivier Fontaine*, Margaret Kosek, Shinjini Bhatnagar, Cynthia Boschi-Pinto, Kit Yee Chan, Christopher Duggan, Homero
Martinez, Hugo Ribeiro, Nigel C. Rollins, Mohammed A. Salam, Mathuram Santosham, John D. Snyder, Alexander C. Tsai,
Beth Vargas, Igor Rudan
hildhood diarrhoea still claims nearly 2 million in different research options, and (iii) the likelihood of
lives each year and remains responsible for 18% of achieving reductions of persisting burden of disease and
all child deaths [1,2]. Regardless of this, research disability through investments. The CHNRI methodology has
C
interest in this disease has been steadily decreasing after three stages: input from investors and policy makers (defining
the development of cost-effective interventions in the 1980s the context and criteria for priority setting); input from
[3]. In addition, the amount of available research funds technical experts (listing and scoring research investment
per disability-adjusted life year (DALY) are several orders options); and input from other stakeholders (weighing the
of magnitude lower for diarrhoea when compared to some criteria according to wider societal system of values) [10–12].
other diseases, such as autism or diabetes type 2 [4]. The The aim of this particular implementation of the CHNRI
UN’s Millennium Development Goal #4 (MDG4) states method was to inform key global donors, investors in health
that childhood mortality should be reduced by two thirds research (especially of public funds), and int
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