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Policy Forum Seventy-Five Trials and Eleven Systematic Reviews a Day: How Will We Ever Keep Up? 1 2 3 Hilda Bastian *, Paul Glasziou , Iain Chalmers 1 German Institute for Quality and Efficiency in Health Care (IQWiG), Cologne, Germany, 2 Centre for Research in Evidence-Based Practice, Faculty of Health Sciences, Bond University, Gold Coast, Australia, 3 James Lind Library, James Lind Initiative, Oxford, United Kingdom Thirty years ago, and a quarter of a century after randomised trials had be- Summary Points come widely accepted, Archie Cochrane reproached the medical profession for not N When Archie Cochrane reproached the medical profession for not having having managed to organise a ‘‘critical critical summaries of all randomised controlled trials, about 14 reports of trials summary, by speciality or subspeciality, were being published per day. There are now 75 trials, and 11 systematic adapted periodically, of all relevant ran- reviews of trials, per day and a plateau in growth has not yet been reached. domised controlled trials’’ [1]. Thirty N Although trials, reviews, and health technology assessments have undoubtedly years after Cochrane’s reproach we feel had major impacts, the staple of medical literature synthesis remains the non- it is timely to consider the extent to which systematic narrative review. Only a small minority of trial reports are being health professionals, the public and policy- analysed in up-to-date systematic reviews. Given the constraints, Archie makers could now use ‘‘critical summa- Cochrane’s vision will not be achieved without some serious changes