selection in reported epidemiological risks an empirical assessment选择流行病学报告实证评估风险.pdfVIP

PLoS MEDICINE Selection in Reported Epidemiological Risks: An Empirical Assessment 1 1 1,2* Fotini K. Kavvoura , George Liberopoulos , John P. A. Ioannidis 1 Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece, 2 Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts, United States of America Funding: The authors received no A B S T R A C T specific funding for this study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the Background manuscript. Epidemiological studies may be subject to selective reporting, but empirical evidence thereof Competing Interests: The authors is limited. We empirically evaluated the extent of selection of significant results and large effect have declared that no competing sizes in a large sample of recent articles. interests exist. Academic Editor: Eduardo L. Franco, McGill University, Canada Methods and Findings Citation: Kavvoura FK, Liberopoulos We evaluated 389 articles of epidemiological studies that reported, in their respective G, Ioannidis JPA (2007) Selection in abstracts, at least one relative risk for a continuous risk factor in contrasts based on median, reported epidemiological risks: An tertile, quartile, or quintile categorizations. We examined the proportion and correlates of empirical assessment. PLoS Med 4(3): e79. doi:10.1371/journal.pmed. reporting statistically significant and nonsignificant results