severe sepsis in two ugandan hospitals a prospective observational study of management and outcomes in a predominantly hiv-1 infected population严重脓毒症在两个乌干达医院管理和结果的前瞻性观察性研究主要是hiv - 1感染的人口.pdfVIP
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severe sepsis in two ugandan hospitals a prospective observational study of management and outcomes in a predominantly hiv-1 infected population严重脓毒症在两个乌干达医院管理和结果的前瞻性观察性研究主要是hiv - 1感染的人口
Severe Sepsis in Two Ugandan Hospitals: a Prospective
Observational Study of Management and Outcomes in a
Predominantly HIV-1 Infected Population
1 2 3 2 4
Shevin T. Jacob *, Christopher C. Moore , Patrick Banura , Relana Pinkerton , David Meya , Pius
5 5,6,7 8 9 2
Opendi , Steven J. Reynolds , Nathan Kenya-Mugisha , Harriet Mayanja-Kizza , W. Michael Scheld ,
for the Promoting Resource-limited Interventions for Sepsis Management in Uganda (PRISM-U) Study
Group
1 Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, United States of America, 2 Division of Infectious
Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, United States of America, 3 Department of
Community Health, Masaka Regional Referral Hospital, Masaka, Uganda, 4 Infectious Diseases Institute, Faculty of Medicine, Makerere University, Mulago Hospital
Complex, Kampala, Uganda, 5 Rakai Health Sciences Program, Kalisizo, Uganda, 6 Department of Intramural Research, National Institutes of Health, Bethesda, Maryland,
United States of America, 7 Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, 8 Uganda Ministry of Health, Kampala, Uganda,
9 Faculty of Medicine, Makerere University, Mulago Hospital Complex, Kampala, Uganda
Abstract
Background: Sepsis likely contributes to the high burden of infectious disease morbidity and mortality in low income
countries. Data regarding sepsis management in sub-Saharan Africa are limited. We conducted a p
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