severity of influenza a 2009 (h1n1) pneumonia is underestimated by routine prediction rules. results from a prospective, population-based study2009年甲型流感(h1n1)肺炎的严重程度由常规的预测低估了规则。.pdfVIP
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severity of influenza a 2009 (h1n1) pneumonia is underestimated by routine prediction rules. results from a prospective, population-based study2009年甲型流感(h1n1)肺炎的严重程度由常规的预测低估了规则。
Severity of Influenza A 2009 (H1N1) Pneumonia Is
Underestimated by Routine Prediction Rules. Results
from a Prospective, Population-Based Study
1,2 1,3 ¨ 1,3 4 2
Agnar Bjarnason , Gudlaug Thorleifsdottir , Arthur Love , Janus F. Gudnason , Hilmir Asgeirsson ,
2 1 5 2
Kristinn L. Hallgrimsson , Berglind S. Kristjansdottir , Gunnsteinn Haraldsson , Olafur Baldursson ,
Karl G. Kristinsson1,5, Magnus Gottfredsson 1,2*
1 Faculty of Medicine, University of Iceland, Reykjavik, Iceland, 2 Department of Medicine, Landspitali University Hospital, Reykjavik, Iceland, 3 Department of Virology,
Landspitali University Hospital, Reykjavik, Iceland, 4 Department of Emergency Medicine, Landspitali University Hospital, Reykjavik, Iceland, 5 Department of Clinical
Microbiology, Landspitali University Hospital, Reykjavik, Iceland
Abstract
Background: Characteristics of patients with community-acquired pneumonia (CAP) due to pandemic influenza A 2009
(H1N1) have been inadequately compared to CAP caused by other respiratory pathogens. The performance of prediction
rules for CAP during an epidemic with a new infectious agent are unknown.
Methods: Prospective, population-based study from November 2008–November 2009, in centers representing 70% of
hospital beds in Iceland. Patients admitted with CAP underwent evaluation and etiologic testing, including polymerase
chain reaction (PCR) for influenza. Data on influenza-like illness in the com
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