介入治疗对冠脉慢性完全闭塞病变患者预后影响.docxVIP

宁夏医科大学硕士研究生学位论文英文摘要The Clinical Outcomes of PercutaneousCoronary Intervention in Chronic Total Coronary OcclusionABSTRACTObjectiveThe purpose of this study was to compare the clinical character, coronaryartery lesion, the left ventricular function, the occurrence of the major adverse cardiac event(MACE) of the chronic total occlusion (CTO) patients who received percutaneous coronaryintervention with those who not received to elucidate the successful percutaneous coronaryintervention (PCI) treatment prediction in patients. Methods271 patients (203male and 68female) with chronic total occlusion were enrolled. Inclusion criteria included both completeocclusions (Thrombolysis In Myocardial Infarction [TIMI] flow grade 0) ,where noanterograde filling beyond the lesion was visible, and functional occlusions (TIMI) flow grade1) ,where a faint, late anterograde flow with incomplete opacification of the distal vessel inthe absence of a discernible lumen channel. Patients with angina or inducible ischemia bySPECT, ETT, Holter were selected for the study. The diameter of the coronary artery lumenmust =2.5 mm and the estimated duration of occlusion must 3 months. Patients wereexcluded for the following reasons: 1. patients with acute myocardial infarction within 3months; 2. cerebrovascular accident within 6 month; 3. severe valvular heart disease, dilatedcardiomyopathy and hypertrophic cardiomyopathy; 4. coagulation dysfunction; 5. chronicrenal or hepatic failure; 6. contraindication to aspirin, clopidogrel or heparin. Depending onwhether the occluded coronary artery was reopened, the patients were divided into PCIsuccess group (n=178) and unsuccess group (n=93). We adopt regular outpatient clinic andtelephone followup, the daily activities,the number of Angina, Cardiac Function ,cardiacevents and cerebral of two groups were observed. All the data were analysed by SPSS11.5III宁夏医科大学硕士研究生学位论文英文摘要statistics software, P value 0.05 was considered to have statistical significance. Re