52例小儿静滴阿奇霉素不良反应观察及护理.docVIP

52例小儿静滴阿奇霉素不良反应观察及护理 　【摘要】 目的：探讨预防小儿静滴阿奇霉素不良反应发生的护理对策，保证患儿用药安全。方法：选取在笔者所在科进行静脉滴注阿奇霉素的52例小儿患者为研究对象，对用药可能出现的不良反应进行临床护理，观察不良反应发生情况。结果：52例静脉滴注阿奇霉素小儿患者中，1例出现过敏反应，8例出现轻度的肠胃不适，3例出现中度的肠胃不适，1例出现重度的肠胃不适，3例出现局部皮肤反应，不良反应发生率为30.8%，经相应处理后，不良反应消失。结论：加强患儿用药过程中不良反应的观察，采取相应的护理干预能最大限度的减轻或消除不良反应，提高临床疗效和用药安全。　　【关键词】 阿奇霉素； 小儿不良反应； 护理　　中图分类号 R473.72 文献标识码 B 文章编号 1674-6805（2016）27-0067-02　　Observation and Nursing of Adverse Reaction of Intravenous Azithromycin in 52 Children/DUAN Ji-yun，FAN Li-ping.//Chinese and Foreign Medical Research，2016，14（27）：67-68　　【Abstract】 Objective：To explore the the nursing measures to prevent the adverse reaction of intravenous Azithromycin in children，so as to ensure the safety of medication in children.Method：52 cases of pediatric patients with intravenous infusion of Azithromycin in our department were selected as the study objects.The clinical nursing for the adverse reactions that might occur in the treatment was used.The situation of adverse reactions were observed.Result：In the 52 patients with intravenous infusion of Azithromycin，allergic reaction occurred in 1 case，8 cases had mild gastrointestinal discomfort，3 cases had moderate gastrointestinal discomfort，1 case had severe gastrointestinal discomfort，local skin reactions occurred in 3 cases，the incidence rate of adverse reactions was 30.8%.After appropriate treatment，the adverse reactions disappeared.Conclusion：Strengthening the observation of adverse reactions in the process of drug use，taking appropriate nursing intervention can reduce or eliminate the adverse reactions to the greatest extent，improve the clinical efficacy and safety of medication.　　【Key words】 Azithromycin； Adverse reactions in children； Nursing　　First-authors address：The Third Affiliated Hospital of Xuzhou Medical College，Xuzhou 221003，China　　doi：10.14033/j.cnki.cfmr.2016.27.034　　阿奇霉素是在红霉素的基础上经过化学结构修饰形成的新一代广谱抗生素，通过阻碍细菌转肽酶过程而抑制细菌蛋白质合成。由于阿奇霉素具有对酸稳定，半衰期长，而且感染部位组织及细胞内浓度较高，疗效显著，无须做过敏试验，安全性和耐受性好等优点[1]，广泛应用于临床，但仍然会出现一些不良反应，如过敏反应、肠胃道反应和局