42nd annual meeting of the american society for cell biology, san francisco, california, usa, 14–18 december 2002第42任美国细胞生物学学会的年度会议上,旧金山,加利福尼亚,美国,2002年12月14 - 18.pdfVIP

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42nd annual meeting of the american society for cell biology, san francisco, california, usa, 14–18 december 2002第42任美国细胞生物学学会的年度会议上,旧金山,加利福尼亚,美国,2002年12月14 - 18.pdf

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42nd annual meeting of the american society for cell biology, san francisco, california, usa, 14–18 december 2002第42任美国细胞生物学学会的年度会议上,旧金山,加利福尼亚,美国,2002年12月14 - 18

Available online /content/5/3/147 Meeting report 42nd Annual Meeting of the American Society for Cell Biology, San Francisco, California, USA, 14–18 December 2002 Paraic A Kenny and Aylin Rizki Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA Corresponding author: Aylin Rizki (e-mail: arizki@) Published: 11 March 2003 Breast Cancer Res 2003, 5:147-153 (DOI 10.1186/bcr590) © 2003 BioMed Central Ltd (Print ISSN 1465-5411; Online ISSN 1465-542X) Abstract The Annual Meeting of the American Society for Cell Biology (ASCB) is a diverse conference covering all topics in cell biology. While all of the basic biology presented at this meeting may potentially contribute to breast cancer research, there were a significant number of presentations and posters directly pertinent to this field. Here we have summarized the research that is of greatest immediate relevance to breast cancer, with particular emphasis on mammary gland development and tumorigenesis in vivo, three-dimensional in vitro models of mammary morphogenesis, alterations of signal transduction pathways in breast cancer, and global studies in expression profiling and drug screening. Keywords: basement membrane, breast cancer, matrix metalloproteinase, metastasis, signal transduction Introduction winners, Avram Hershko, Alexander Varshavsky, Kathleen During a rainy, windswept San Francisco week in mid- Collins, Frank Talamantes, Benjamin Cravatt, Eric December, over 8000 scientists found shelter at the 42nd Wieschaus, Natasha Raikhel, and Clare Waterman-Storer. annual meeting of the Amer