an improved empirical bayes approach to estimating differential gene expression in microarray time-course data betr (bayesian estimation of temporal regulation)一种改进的经验贝叶斯估计微分方法在微阵列基因表达时间进程数据betr(贝叶斯估计的时间管理).pdfVIP
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BMC Bioinformatics BioMed Central
Research article Open Access
An improved empirical bayes approach to estimating differential
gene expression in microarray time-course data: BETR (Bayesian
Estimation of Temporal Regulation)
1 2 2 3
Martin J Aryee , José A Gutiérrez-Pabello , Igor Kramnik , Tapabrata Maiti
and John Quackenbush*1,4
Address: 1Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, Massachusetts 02115, USA, 2Department
of Immunology and Infectious Diseases, Harvard School of Public Health, 655 Huntington Avenue, Boston, Massachusetts 02115, USA,
3Department of Statistics and Probability, Michigan State University, East Lansing, Massachusetts 48824, USA and 4Department of Biostatistics
and Computational Biology and Department of Cancer Biology, Dana-Farber Cancer Institute, 44 Binney St, Boston, Massachusetts 02115, USA
Email: Martin J Aryee - aryee@; José A Gutiérrez-Pabello - jagp@servidor.unam.mx; Igor Kramnik - ikramnik@;
Tapabrata Maiti - maiti@; John Quackenbush* - johnq@
* Corresponding author
Published: 10 December 2009 Received: 10 June 2009
Accepted: 10 December 2009
BMC Bioinformatics 2009, 10:409 doi:10.1186/1471-2105-10-409
This article is available from: /1471-2105/10/409
© 2009 Aryee et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium,
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