analysis of proteins with the hot dog fold prediction of function and identification of catalytic residues of hypothetical proteins分析u201c热狗u201d的蛋白质折叠预测催化残基函数和识别的假想的蛋白质.pdfVIP

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analysis of proteins with the hot dog fold prediction of function and identification of catalytic residues of hypothetical proteins分析u201c热狗u201d的蛋白质折叠预测催化残基函数和识别的假想的蛋白质.pdf

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analysis of proteins with the hot dog fold prediction of function and identification of catalytic residues of hypothetical proteins分析u201c热狗u201d的蛋白质折叠预测催化残基函数和识别的假想的蛋白质

BMC Structural Biology BioMed Central Research article Open Access Analysis of proteins with the hot dog fold: Prediction of function and identification of catalytic residues of hypothetical proteins 1 1 1 Lakshmi S Pidugu , Koustav Maity , Karthikeyan Ramaswamy , 2 1 Namita Surolia and Kaza Suguna* Address: 1Molecular Biophysics Unit, Indian Institute of Science, Bangalore, 560 012, India and 2Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, 560 064, India Email: Lakshmi S Pidugu - plsmukhi@; Koustav Maity - koustav@mbu.iisc.ernet.in; Karthikeyan Ramaswamy - Karthikeyan_Ramaswamy@S; Namita Surolia - surolia@jncasr.ac.in; Kaza Suguna* - suguna@mbu.iisc.ernet.in * Corresponding author Published: 28 May 2009 Received: 25 November 2008 Accepted: 28 May 2009 BMC Structural Biology 2009, 9:37 doi:10.1186/1472-6807-9-37 This article is available from: /1472-6807/9/37 © 2009 Pidugu et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The hot dog fold has been found in more than sixty proteins since the first report of its existence about a decade ago. The fold appears to have a strong a