原创力文档are risk estimates biased in follow-up studies of psychosocial factors with low base-line participation是风险较低的估计偏差在后续研究社会心理因素基线参与.pdfVIP
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are risk estimates biased in follow-up studies of psychosocial factors with low base-line participation是风险较低的估计偏差在后续研究社会心理因素基线参与
Kaerlev et al. BMC Public Health 2011, 11:539
/1471-2458/11/539
RESEARCH ARTICLE Open Access
Are risk estimates biased in follow-up studies of
psychosocial factors with low base-line participation?
1,2,3* 1 4 5 1
Linda Kaerlev , Henrik A Kolstad , Åse Marie Hansen , Jane Frølund Thomsen , Anette Kærgaard ,
4 5 1 6 1
Reiner Rugulies , Sigurd Mikkelsen , Johan Hviid Andersen , Ole Mors , Matias B Grynderup and
Jens Peter Bonde5
Abstract
Background: Low participation in population-based follow-up studies addressing psychosocial risk factors may
cause biased estimation of health risk but the issue has seldom been examined. We compared risk estimates for
selected health outcomes among respondents and the entire source population.
Methods: In a Danish cohort study of associations between psychosocial characteristics of the work environment
and mental health, the source population of public service workers comprised 10,036 employees in 502 work units
of which 4,489 participated (participation rate 45%). Data on the psychosocial work environment were obtained for
each work unit by calculating the average of the employee self-reports. The average values were assigned all
employees and non-respondent at the work unit. Outcome data on sick leave and prescription of antidepressant
medication during the follow-up period (1.4.2007-31.12.2008) was obtained by linkage to national registries.
Results: Respondents differed at baseline from non-respondents by gender, age, employment status, sick leave
and hospitalization for affective disorders. However, risk estimates for sick leave and
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