原创力文档assessment of the diagnostic sensitivity and specificity of an indirect elisa kit for the diagnosis of brucella ovis infection in rams评估诊断敏感性和特异性的一种间接酶联免疫试剂盒在公羊羊属布鲁氏菌感染的诊断.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
assessment of the diagnostic sensitivity and specificity of an indirect elisa kit for the diagnosis of brucella ovis infection in rams评估诊断敏感性和特异性的一种间接酶联免疫试剂盒在公羊羊属布鲁氏菌感染的诊断
Praud et al. BMC Veterinary Research 2012, 8:68
/1746-6148/8/68
RESEARCH ARTICLE Open Access
Assessment of the diagnostic sensitivity and
specificity of an indirect ELISA kit for the
diagnosis of Brucella ovis infection in rams
1 2 3 3 4 3*
Anne Praud , Jean-Luc Champion , Yannick Corde , Antoine Drapeau , Laurence Meyer and Bruno Garin-Bastuji
Abstract
Background: Brucella ovis causes an infectious disease responsible for infertility and subsequent economic losses in
sheep production. The standard serological test to detect B. ovis infection in rams is the complement fixation test
(CFT), which has imperfect sensitivity and specificity in addition to technical drawbacks. Other available tests include
the indirect enzyme-linked immunosorbent assays (I-ELISA) but no I-ELISA kit has been fully evaluated.
The study aimed to compare an I-ELISA kit and the standard CFT. Our study was carried out on serum samples
from 4599 rams from the South of France where the disease is enzootic. A Bayesian approach was used to estimate
tests characteristics (diagnostic sensitivity, Se and diagnostic specificity, Sp). The tests were then studied together
in order to optimise testing strategies to detect B. ovis.
Results: After optimising the cut-off values in order to avoid doubtful results without deteriorating the
concordance between the results of the two tests, the I-ELISA appeared to be slightly more sensitive than CFT
(Se I-ELISA = 0.917 [0.822; 0.992], 95% Credibility Interval (CrI) compared to Se CFT = 0.860 [0.740; 0.967], 95% CrI).
However, CFT was slightly more specific than I-ELISA (Sp CFT = 0.988 [0.947; 1.0], 95% CrI) compared to
Sp I-ELISA =0.952 [0.901; 1.0],
您可能关注的文档
- are the pneumococcal polysaccharide vaccines effective meta-analysis of the prospective trials肺炎球菌多糖疫苗有效的荟萃分析的前瞻性试验.pdf
- are waiting times for hospital admissions affected by patients' choices and mobility等待时间是影响住院病人的选择和灵活性.pdf
- are variations in rates of attending cultural activities associated with population health in the united states在利率变化与人口健康相关的参加文化活动在美国.pdf
- are we there yet australian road safety targets and road traffic crash fatalities我们还澳大利亚道路安全目标和道路交通事故死亡人数.pdf
- are we her-ting for innovation in neoadjuvant breast cancer trial design我们创新her-ting乳腺癌新辅助试验设计.pdf
- are women and providers satisfied with antenatal care views on a standard and a simplified, evidence-based model of care in four developing countries是女性和提供者满意标准和一个简化的产前保健的观点,循证护理模式在四个发展中国家.pdf
- are youth mentoring programs good value-for-money an evaluation of the big brothers big sisters melbourne program青年辅导项目好认钱不认人的评价大兄弟姐妹墨尔本计划.pdf
- are workplace health promotion programs effective at improving presenteeism in workers a systematic review and best evidence synthesis of the literature工作场所健康促进项目有效地改善工人的现象系统回顾和最佳证据合成的文献.pdf
- arena3d visualizing time-driven phenotypic differences in biological systemsarena3d可视化一个完全时间驱动表型差异的生物系统项目.pdf
- arf6 recruits the rac gef kalirin to the plasma membrane facilitating rac activationarf6新兵的rac gef kalirin质膜促进rac激活.pdf
- assessment of the capacity to consent to treatment in patients admitted to acute medical wards评估的能力同意治疗急性医疗病房收治的病人.pdf
- assessment of surfactant use in preterm infants as a marker of neonatal intensive care unit quality表面活性剂在早产儿中使用的评估质量新生儿重症监护病房的一个标志.pdf
- assessment of equine autoimmune thrombocytopenia (eat) by flow cytometry马的评估自身免疫性血小板减少症(吃)流式细胞术.pdf
- assessment of the direct medical costs of diabetes mellitus and its complications in the united arab emirates评估糖尿病及其并发症的直接医疗费用在阿拉伯联合酋长国.pdf
- assessment of the feasibility of exon 45–55 multiexon skipping for duchenne muscular dystrophy外显子的可行性评估45 - 55 multiexon跳过杜氏肌肉营养不良症.pdf
- assessment of the effect of betaine on p16 and c-myc dna methylation and mrna expression in a chemical induced rat liver cancer model评估的影响甜菜碱p16和原癌基因dna甲基化和mrna表达化学诱导大鼠肝癌模型.pdf
- assessment of the multidisciplinary education for a major change in clinical practice; a prospective cohort study多学科教育的评估在临床实践中重大变化;.pdf
- assessment of the health care waste generation rates and its management system in hospitals of addis ababa, ethiopia, 2011评估医疗废物产生率和亚的斯亚贝巴的管理系统在医院,埃塞俄比亚,2011.pdf
- assessment of the medicinal potentials of the methanol extracts of the leaves and stems of buddleja saligna甲醇提取物的药用潜力评估的叶子和茎buddleja saligna.pdf
- assessment of surfactant protein a (sp-a) dependent agglutination评估的表面活性剂蛋白(sp-a)相关的凝集.pdf
文档评论（0）