原创力文档association between body size and blood pressure in children from different ethnic origins儿童的体型和血压之间的联系从不同民族的起源.pdfVIP
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association between body size and blood pressure in children from different ethnic origins儿童的体型和血压之间的联系从不同民族的起源
Hoog et al. Cardiovascular Diabetology 2012, 11:136 CARDIO
/content/11/1/136 VASCULAR
DIABETOLOGY
ORIGINAL INVESTIGATION Open Access
Association between body size and blood
pressure in children from different ethnic origins
1,2* 2,3 1 4 1
Marieke LA de Hoog , Manon van Eijsden , Karien Stronks , Reinoud JBJ Gemke and Tanja GM Vrijkotte
Abstract
Objective: To assess associations between body size and blood pressure in children (5-6 years) from different
ethnic origins.
Method: Five ethnic groups of the ABCD cohort were examined: Dutch (n=1 923), Turkish (n=99), Moroccan
(n=187), Black-African (n=67) and Black-Caribbean (n=121). Data on body-mass-index (BMI), waist-to-height ratio
(WHtR), fat-mass-index (FMI), and systolic blood pressure (SBP) and diastolic blood pressure (DBP), were collected.
Linear regression analysis with restricted cubic splines was used to examine non-linear associations between body
size and blood pressure, adjusted for age, sex, height and birth weight.
Results: Ethnic differences were found in associations of BMI with SBP and DBP (SBP: p=0.001 and DBP: p=0.01)
and FMI with SBP (p=0.03). BMI and FMI had a relatively large positive association with SBP in Turkish children
(BMI: β=2.46mmHg; 95%CI:1.20-3.72; FMI: β=2.41mmHg; 95%CI:1.09-3.73) compared to Dutch (BMI: β=1.31mmHg;
95%CI:0.71-1.92; FMI: β=0.84mmHg; 95%CI:0.23-1.45). Black-Caribbean and Moroccan children showed high
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