association between frequent use of nonsteroidal anti-inflammatory drugs and breast cancer联系频繁使用非甾体类抗炎药和乳腺癌.pdfVIP

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association between frequent use of nonsteroidal anti-inflammatory drugs and breast cancer联系频繁使用非甾体类抗炎药和乳腺癌.pdf

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association between frequent use of nonsteroidal anti-inflammatory drugs and breast cancer联系频繁使用非甾体类抗炎药和乳腺癌

BMC Cancer BioMed Central Research article Open Access Association between frequent use of nonsteroidal anti-inflammatory drugs and breast cancer 1 1 1 1,2 Elham Rahme* , Joumana Ghosn , Kaberi Dasgupta , Raghu Rajan and Marie Hudson1 Address: 1Division of Clinical Epidemiology, McGill University Health Centre Research Institute, Montreal, Canada and 2Division of Medical Oncology, McGill University Health Center, Montreal, Canada Email: Elham Rahme* - elham.rahme@mcgill.ca; Joumana Ghosn - ghosn@iro.umontreal.ca; Kaberi Dasgupta - kaberi.dasgupta@mcgill.ca; Raghu Rajan - raghu.rajan@muhc.mcgill.ca; Marie Hudson - marie.hudson@mail.mcgill.ca * Corresponding author Published: 12 December 2005 Received: 17 June 2005 Accepted: 12 December 2005 BMC Cancer 2005, 5:159 doi:10.1186/1471-2407-5-159 This article is available from: /1471-2407/5/159 © 2005 Rahme et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Eighty percent of all breast cancers and almost 90% of breast cancer deaths occur among post-menopausal women. We used a nested case control design to examine the association between nonsteroidal anti-inflammatory drug (NSAID)