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association of adam33 gene polymorphisms with adult allergic asthma and rhinitis in a chinese han population协会adam33基因多态性与中国汉族成人过敏性哮喘和鼻炎.pdf

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association of adam33 gene polymorphisms with adult allergic asthma and rhinitis in a chinese han population协会adam33基因多态性与中国汉族成人过敏性哮喘和鼻炎

BMC Medical Genetics BioMed Central Research article Open Access Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population †1 †2 3 1 2 Dongju Su , Ximei Zhang , Hong Sui , Fuzhen Lü* , Lianhong Jin* and Jing Zhang1 Address: 1Department of Respiratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, PR China, 2Department of Histology and Embryology, Harbin Medical University, Harbin 150086, PR China and 3Department of Statistics, Harbin Medical University, Harbin 150086, PR China Email: Dongju Su - sudongju@; Ximei Zhang - ximei1119@; Hong Sui - suisuihong@126.com; Fuzhen Lü* - yyhhww@; Lianhong Jin* - zx2005@; Jing Zhang - m88512@ * Corresponding authors †Equal contributors Published: 9 September 2008 Received: 15 May 2008 Accepted: 9 September 2008 BMC Medical Genetics 2008, 9:82 doi:10.1186/1471-2350-9-82 This article is available from: /1471-2350/9/82 © 2008 Su et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Rhinitis and asthma are very common diseases involving genetic and environmental factors. Most patients with asthma also have rhinitis, which suggests the concept of one