automatic categorization of diverse experimental information in the bioscience literature自动分类的不同实验在生物科学文献信息.pdfVIP

Fang et al. BMC Bioinformatics 2012, 13:16 /1471-2105/13/16 METHODOLOGY ARTICLE Open Access Automatic categorization of diverse experimental information in the bioscience literature 1 1 1 1 1 1 Ruihua Fang , Gary Schindelman , Kimberly Van Auken , Jolene Fernandes , Wen Chen , Xiaodong Wang , 2 2 3 3 4 4 Paul Davis , Mary Ann Tuli , Steven J Marygold , Gillian Millburn , Beverley Matthews , Haiyan Zhang , Nick Brown5, William M Gelbart4 and Paul W Sternberg1* Abstract Background: Curation of information from bioscience literature into biological knowledge databases is a crucial way of capturing experimental information in a computable form. During the biocuration process, a critical first step is to identify from all published literature the papers that contain results for a specific data type the curator is interested in annotating. This step normally requires curators to manually examine many papers to ascertain which few contain information of interest and thus, is usually time consuming. We developed an automatic method for identifying papers containing these curation data types among a large pool of published scientific papers based on the machine learning method Support Vector Machine (SVM). This classification system is completely automatic and can be readily applied to diverse experimental data types. It has been in use in production for automatic categorization of 10 different experimental datatypes in the biocuration process at WormBase for the past two years and it is in the process of being adopted in the biocuration process at FlyBase and the Saccharomyces Genome Database (SGD). W