原创力文档detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the state of s？o paulo, brazil检测猪圆环病毒基因型2 a和2 b的流产胎儿感染猪群的年代圣保罗,巴西.pdfVIP
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detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the state of s？o paulo, brazil检测猪圆环病毒基因型2 a和2 b的流产胎儿感染猪群的年代圣保罗,巴西
Castro et al. Acta Veterinaria Scandinavica 2012, 54:29
/content/54/1/29
BRIEF COMMUNICATION Open Access
Detection of porcine circovirus genotypes 2a and
2b in aborted foetuses from infected swine herds
in the State of São Paulo, Brazil
1* 2 1 2 1
Alessandra MMGdeCastro , Taís F Cruz , Vanessa R Salgado , Tatiana M Kanashiro , Karen L Ferrari ,
João P AraujoJr2, Paulo E Brandão1 and Leonardo J Richtzenhain1
Abstract
Background: Porcine circovirus type 2 (PCV2) has been associated with several disease complexes, including
reproductive failure. The aim of this study was to identify the subtypes of PCV2 that are associated with
reproductive failure in pigs from the State of São Paulo, Brazil and to investigate co-infections with other infectious
organisms.
Findings: Samples of 168 aborted foetuses or mummified foetuses from five farrow-to-finish swine farms known to
be infected with PCV2 and located in the State of São Paulo were tested for PCV2 by polymerase chain reaction
(PCR). Positive samples were additionally tested for porcine parvovirus (PPV), Leptospira spp. and Brucella spp. by
PCR. PCV2 was detected in 18 of the samples (10.7%). PPV, Brucella spp. and Leptospira spp were found in 2, 10 and
0 cases, respectively. Eleven PCV2 strains were sequenced and determined to be either genotype 2a (n = 1) or 2b
(n = 10).
Conclusions: The findings indicate that the frequency of PCV2 infections in aborted porcine foetuses from the State
of São Paulo is rather low (10.7%) and that co-infection with other pathogens is common and may be involved in
PCV2 associated reproductive failure. No repeatable, characteristic amino acid motifs for regions of the PCV2 capsid
protein seemed to be associated with
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