evaluation of the swedish breeding program for cavalier king charles spaniels瑞典繁殖计划的评估对于骑士查理王猎犬.pdfVIP
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evaluation of the swedish breeding program for cavalier king charles spaniels瑞典繁殖计划的评估对于骑士查理王猎犬
Lundin and Kvart Acta Veterinaria Scandinavica 2010, 52:54
/content/52/1/54
RESEARCH Open Access
Evaluation of the Swedish breeding program for
cavalier King Charles spaniels
1 2*
Tobias Lundin , Clarence Kvart
Abstract
A breeding program with the aim of reducing the prevalence of mitral regurgitation (MR) caused by myxomatous
mitral valve disease (MMVD) in Cavalier King Charles Spaniels (CKCS) is currently ongoing in Sweden. In this investi-
gation 353 CKCS were selected as a sample of the population and 150 were examined by auscultation for heart
murmurs when they reached the age of six years in 2007 and 2009. The aim with this investigation was to study
the prevalence of heart murmurs in six-year-old CKCS and to estimate if prevalence has decreased since the breed-
ing program was introduced 2001. The effect of the breeding program was evaluated by comparing the preva-
lence of heart murmurs in the two groups. In 2007, the prevalence of heart murmurs was 52% (50% for females
and 54% for males) and in 2009, the prevalence was 55% (44% for females and 67% for males). No significant dif-
ference was found in the prevalence of heart murmurs between 2007 and 2009 (P = 0.8). For all six-year-old CKCS,
the prevalence of heart murmur was 53% (females 46% and males 61%), which is higher than previous Swedish
investigations.
Background MR caused by MMVD, and at the age of 6-7 years,
Mitral regurgitation (MR), secondary to myxomatous murmur prevalence is approximately 50%. At the age of
mitral valve disease (MMVD), is the most common car- 11 years, almost 100% of CKCS have developed MMVD
diac disorder in dogs and is usually caused by progres- [3-8].
siv
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