原创力文档high incidence of epstein-barr virus, cytomegalovirus and human herpesvirus 6 infections in children with cancer高发病率的巴尔病毒、巨细胞病毒和人类疱疹病毒6感染在儿童癌症.pdfVIP
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high incidence of epstein-barr virus, cytomegalovirus and human herpesvirus 6 infections in children with cancer高发病率的巴尔病毒、巨细胞病毒和人类疱疹病毒6感染在儿童癌症
BMC Pediatrics BioMed Central
BMC Pediatrics 2
2002,
Research article
High incidence of Epstein-Barr virus, cytomegalovirus and human
herpesvirus 6 infections in children with cancer
1 2
Jaroslav Michálek * and Radek Horvath
Address: 1Department of Pediatrics, Division of Hematology/Oncology, Masaryk University, Brno, Czech Republic and 2Laboratory of Genetics
and Molecular Biology, Center for Cardiovascular and Transplant Surgery, Brno, Czech Republic
E-mail: Jaroslav Michálek* - jaroslav.michalek@; Radek Horvath - horvathr@seznam.cz
*Corresponding author
Published: 10 January 2002 Received: 4 August 2001
Accepted: 10 January 2002
BMC Pediatrics 2002, 2:1
This article is available from: /1471-2431/2/1
© 2002 Michálek and Horvath; licensee BioMed Central Ltd. Verbatim copying and redistribution of this article are permitted in any medium for any
non-commercial purpose, provided this notice is preserved along with the articles original URL. For commercial use, contact info@
Abstract
Background: A prospective single-center study was performed to study infection with
lymphotropic herpesviruses (LH) Epstein-Barr virus (EBV), cytomegalovirus (CMV) and human
herpesvirus 6 (HHV-6) in children with cancer.
Methods: The group of 186 children was examined for the presence of LH before, during and 2
months after the end of anticancer treatment. Serology of EBV and CMV was monitored in all
children, serology of HHV-6 and
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