原创力文档hiv, appendectomy and postoperative complications at a reference hospital in northwest tanzania cross-sectional study参考医院的艾滋病,阑尾切除术,术后并发症在坦桑尼亚西北部的横断面研究.pdfVIP
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hiv, appendectomy and postoperative complications at a reference hospital in northwest tanzania cross-sectional study参考医院的艾滋病,阑尾切除术,术后并发症在坦桑尼亚西北部的横断面研究
Giiti et al. AIDS Research and Therapy 2010, 7:47
/content/7/1/47
RESEARCH Open Access
HIV, appendectomy and postoperative
complications at a reference hospital in
Northwest Tanzania: cross-sectional study
1 2* 3,4 1
Geofrey C Giiti , Humphrey D Mazigo , Jorg Heukelbach , William Mahalu
Abstract
Background: Appendicitis is a frequent surgical emergency worldwide. The present study was conducted to
determine the prevalence of HIV, and the association of infection with clinical, intraoperative and histological
findings and outcome, among patients with appendicitis.
Methods: We performed a cross sectional study at Weill-Bugando Medical Centre in northwest Tanzania. In total,
199 patients undergoing appendectomy were included. Demographic characteristics of patients, clinical features,
laboratory, intraoperative and histopathological findings, and HIV serostatus were recorded.
Results: In total, 26/199 (13.1%) were HIV-seropositive. The HIV-positive population was significantly older (mean
age: 38.4 years) than the HIV-negative population (25.3 years; p 0.001). Leukocytosis was present in 87% of
seronegative patients, as compared to 34% in seropositive patients (p = 0.0001), and peritonitis was significantly
more frequent among HIV-positives (31% vs. 2%; p 0.001). The mean (SD) length of hospital stay was significantly
longer in HIV-positives (7.12 ± 2.94 days vs. 4.02 ± 1.14 days; p 0.001); 11.5% of HIV patients developed surgical
site infections, as compared to 0.6% in the HIV-negative group (p = 0.004).
Conclusion: HIV infections are common among patients with appendicitis in Tanzania, and are associated with
severe morbidity, postoperative complications and longer hospital stays. Early diagnosis of a
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