intestinal spirochetosis mimicking inflammatory bowel disease in children肠道螺旋体病模仿儿童炎症性肠病.pdfVIP
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intestinal spirochetosis mimicking inflammatory bowel disease in children肠道螺旋体病模仿儿童炎症性肠病
Helbling et al. BMC Pediatrics 2012, 12:163
/1471-2431/12/163
CASE REPORT Open Access
Intestinal Spirochetosis mimicking inflammatory
bowel disease in children
1 2 3 4 1*
Rossana Helbling , Maria-Chiara Osterheld , Bernard Vaudaux , Katia Jaton and Andreas Nydegger
Abstract
Background: Intestinal spirochetosis is an unusual infection in children and its clinical significance in humans is
uncertain. The presence of these microorganisms in humans is well-known since the late 1800’s and was first
described in 1967 by Harland and Lee by electron microscopy.
Case presentation: This article reports the findings of one pediatric case, review of the current literature, and an
overview of therapeutic options.
Conclusion: A high degree of suspicion is required in cases presenting with abdominal pain, chronic diarrhoea
and/or hematochezia associated with a normal endoscopic examination, thus emphasizing the importance of
multiple biopsies throughout the colon.
Keywords: Intestinal spirochetosis, Brachyspira aalborgi, Brachyspira pilosicoli, Inflammatory bowel disease
Background blood-stained diarrhoea, associated with urgency, weight
Spirochetes are well-known pathogens in veterinary medi- loss of 1.5kg and asthenia. He had no complaint of ab-
cine. They are associated with diarrheal illness, malnutri- dominal pain, fever or anorexia. The onset of symptoms
tion and failure to thrive in a wide range of animals coincided with the end of a 4-day history of acute
(swine, poultry, dogs, cats, opossum, non-human primates gastroenteritis.
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