n-(4-methylsulfonamido-3-phenoxyphenyl)-9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximide10-dihydro-9 n -(4-methylsulfonamido-3-phenoxyphenyl)9日,10-ethanoanthracene-11 12-dicarboximide.pdfVIP

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n-(4-methylsulfonamido-3-phenoxyphenyl)-9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximide10-dihydro-9 n -(4-methylsulfonamido-3-phenoxyphenyl)9日,10-ethanoanthracene-11 12-dicarboximide.pdf

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n-(4-methylsulfonamido-3-phenoxyphenyl)-9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximide10-dihydro-9 n -(4-methylsulfonamido-3-phenoxyphenyl)9日,10-ethanoanthracene-11 12-dicarboximide

Molbank 2011, M740; doi:10.3390/M740 OPEN ACCESS molbank ISSN 1422-8599 /journal/molbank Short Note N-(4-Methylsulfonamido-3-phenoxyphenyl)-9,10-dihydro- 9,10-ethanoanthracene-11,12-dicarboximide 1 2 2 3 Kavitha Kankanala , Varsha Prakash , Khagga Mukkanti , Vangala Ranga Reddy and Sarbani Pal 1,* 1 MNR Degree PG College, Kukatpally, Hyderabad-500085, A. P., India 2 Centre for chemical Sciences and Technology, Institute of Science Technology, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad-500085, A. P., India 3 Dr. Reddy’s Laboratories Ltd., IPDO, Bachupally, Hyderabad-500085, India * Author to whom correspondence should be addressed; E-Mail: Sarbani277@. Received: 7 September 2011 / Accepted: 30 September 2011 / Published: 14 October 2011 Abstract: The title compound, N-(4-methylsulfonamido-3-phenoxyphenyl)-9,10-dihydro- 9,10-ethanoanthracene-11,12-dicarboximide was synthesized in high yield by reaction of N-(4-amino-2-phenoxyphenyl)methanesulfonamide and 9,10-dihydroanthracene-9,10- endo-α,β-succinic anhydride in glacial acetic acid. The structure of the compound was fully characterized by IR, 1H and 13C NMR, mass spectral analysis and elemental analysis. Keywords: sulfonamide; cyclic imide; nimesulide Cyclic imides A (Scheme 1) represent an important class of bioactive molecules that shows a wide range of pharmacological activities such as