n-acyl homoserine lactone production by klebsiella pneumoniae isolated from human tongue surfacen -高丝氨酸内酯生产的肺炎克雷伯菌分离人体舌头表面.pdfVIP

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n-acyl homoserine lactone production by klebsiella pneumoniae isolated from human tongue surfacen -高丝氨酸内酯生产的肺炎克雷伯菌分离人体舌头表面.pdf

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n-acyl homoserine lactone production by klebsiella pneumoniae isolated from human tongue surfacen -高丝氨酸内酯生产的肺炎克雷伯菌分离人体舌头表面

Sensors 2012, 12, 3472-3483; doi:10.3390/s120303472 OPEN ACCESS sensors ISSN 1424-8220 /journal/sensors Article N-Acyl Homoserine Lactone Production by Klebsiella pneumoniae Isolated from Human Tongue Surface 1 2 1 1 3 Wai-Fong Yin , Kathiravan Purmal , Shenyang Chin , Xin-Yue Chan , Chong-Lek Koh , Choon-Kook Sam 3 and Kok-Gan Chan 1,* 1 Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia; E-Mails: yinwaifong@ (W.-F.Y.); shenyang86@ (S.C.); evepy88@ (X.-Y.C.) 2 School of Dental Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia; E-Mail: drkathi@.my 3 Natural Sciences and Science Education AG, National Institute of Education, Nanyang Technological University, 1 Nanyang Walk, 637616, Singapore; E-Mails: chonglek.koh@.sg (C.-L.K.); choonkook.sam@.sg (C.-K.S.) * Author to whom correspondence should be addressed; E-Mail: kokgan@.my; Tel.: +603-7967-5162; Fax: +603-7967-4509. Received: 12 January 2012; in revised form: 16 February 2012 / Accepted: 23 February 2012 / Published: 12 March 2012 Abstract: Bacteria communicate by producing quorum sensing molecules called autoinducers, which include autoinducer-1, an N-hexanoyl homoserine lactone (AHL), and autoinducer-2. Bacteria present in the human oral cavity have been shown to produce autoinducer-2,