原创力文档ola-drb1 microsatellite variants are associated with ovine growth and reproduction traitsola-drb1微卫星变异与绵羊的生长和繁殖特征.pdfVIP
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ola-drb1 microsatellite variants are associated with ovine growth and reproduction traitsola-drb1微卫星变异与绵羊的生长和繁殖特征
Genet. Sel. Evol. 38 (2006) 431–444 431
c
INRA, EDP Sciences, 2006
DOI: 10.1051/gse:2006013
Original article
OLA-DRB1 microsatellite variants
are associated with ovine growth
and reproduction traits
∗
Hermann G , Manzoor R. M, Andreas W. K,
Heinz B
Department of Animal Breeding and Biotechnology, University of Hohenheim,
D-70593 Stuttgart, Germany
(Received 22 March 2005; accepted 8 February 2006)
Abstract – The DRB1 intron 2 (GT) (GA) microsatellite was genotyped in experimental
n m
flocks of seven Merinoland rams and 249 ewes as well as their offspring (381 lambs) from con-
secutive lambings. A total of 16 DRB1 alleles were detected, ranging between 353 and 857 bp.
In comparison with carriers of other alleles, the ewes carrying the predominant 411 bp allele had
higher values of all the recorded fertility traits. For ewes carrying the 394 and 857 bp alleles, the
birth weight of lambs was about 400 g higher as compared to the residual group of ewes. The
observed associations could be due to differences in disease resistance, cell recognition or tissue
differentiation between carriers of various MHC haplotypes which can in turn affect individual
fertility and growth performance.
DRB1 / microsatell
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