原创力文档prevalence of adrenal masses in japanese patients with type 2 diabetes mellitus对肾上腺肿瘤患病率在日本的2型糖尿病患者.pdfVIP
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prevalence of adrenal masses in japanese patients with type 2 diabetes mellitus对肾上腺肿瘤患病率在日本的2型糖尿病患者
Hiroi et al. Diabetology Metabolic Syndrome 2010, 2:71
DIABETOLOGY
/content/2/1/71
METABOLIC SYNDROME
RESEARCH Open Access
Prevalence of adrenal masses in Japanese
patients with type 2 diabetes mellitus
1* 1 1 1,2 3 2 1
Naoki Hiroi , Mariko Sue , Aya Yoshihara , Takamasa Ichijo , Mayumi Yoshida-Hiroi , Mariko Higa , Gen Yoshino
Abstract
Introduction: To date, there have been no reports on the prevalence of adrenal masses in type 2 diabetic
patients. The present study aimed to evaluate the prevalence of adrenal incidentaloma in type 2 diabetic patients
in Japan.
Subjects: We retrospectively evaluated the presence of adrenal masses using abdominal CT scans in 304 type 2
diabetic patients. In those with adrenal masses, we examined the hormone production capacity of the adrenal mass.
Results: Fourteen patients (4.6%) had an adrenal mass. Hormonal analysis identified one case as having subclinical
Cushing’s syndrome, two with primary aldosteronism. Eleven cases had non-functioning masses.
Discussion: The reported prevalence of adrenal incidentaloma in normal subjects is 0.6-4.0% in abdominal CT scan
series. Our results show a relatively high prevalence of adrenal tumors in diabetic patients. On the other hand, the
frequency of functional adenoma in diabetic patients is 21.4%, which is similar to that of normal subjects.
Conclusion: Although further studies are needed to evaluate the prevalence of adrenal tumors in diabetic patients,
our data suggest that evaluation
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