primary mesenchymal chondrosarcoma of the kidney with synchronous implant and infiltrating urothelial carcinoma of the ureter初级的肾间质软骨肉瘤同步植入和渗透的输尿管移行细胞癌.pdfVIP
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primary mesenchymal chondrosarcoma of the kidney with synchronous implant and infiltrating urothelial carcinoma of the ureter初级的肾间质软骨肉瘤同步植入和渗透的输尿管移行细胞癌
Xu et al. Diagnostic Pathology 2012, 7:125
/content/7/1/125
CASE REPORT Open Access
Primary mesenchymal chondrosarcoma of the
kidney with synchronous implant and infiltrating
urothelial carcinoma of the ureter
1 1 2 2*
Hua Xu , MuMin Shao , HuiLi Sun and ShunMin Li
Abstract
Primary mesenchymal chondrosarcoma of the kidney is rare, and it shows distinct undifferentiated tumor cells and
well differentiated cartilagenous components. Also assident infiltrating urothelial carcinoma of the ureter is an
extremely rare cancer. We report a case of primary mesenchymal chondrosarcoma occurring in the left kidney with
an ipsilateral and distinct distal ureteric implant, and a coexisting infiltrating urothelial carcinoma of the ureter in a
64-year-old man. Histopathological examination and immunohistochemical studuies showed the classic features of
mesenchymal chondrosarcoma in kidney, as well as a few infiltrating urothelial in ureter. Multitarget fluorescence in
situ hybridization (FISH) suggested that the development of the urothelial carcinoma in the ureter may be triggered
or induced by the chondrosarcoma component. The patient died 2 month after left nephro-ureterectomy. This is
the first reported case of a primary mesenchymal chondrosarcoma of the kidney with coexisting infiltrating
urothelial carcinoma of the ureter.
Virtual Slides: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/
vs/1522835667751019
Keywords: Mesenchymal chondrosarcoma, Urothelial carcinoma, Kidney, Ureter
Background Case presentation
Mesenchymal chondrosarcoma was first reported by A 64-year-old man presented with gross hematuria and
Lic
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