probiotics and gastrointestinal disease successes, problems and future prospects益生菌和胃肠道疾病的成功,问题和未来前景.pdfVIP

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probiotics and gastrointestinal disease successes, problems and future prospects益生菌和胃肠道疾病的成功,问题和未来前景.pdf

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probiotics and gastrointestinal disease successes, problems and future prospects益生菌和胃肠道疾病的成功,问题和未来前景

Gut Pathogens BioMed Central Review Open Access Probiotics and gastrointestinal disease: successes, problems and future prospects Eamonn P Culligan2,3, Colin Hill2,3 and Roy D Sleator*1,2 Address: 1Department of Biological Sciences, Cork Institute of Technology, Rossa Avenue, Bishopstown, Cork, Ireland, 2Alimentary Pharmabiotic Centre, University College Cork, Western Road, Cork, Ireland and 3Department of Microbiology, University College Cork, Western Road, Cork, Ireland Email: Eamonn P Culligan - eamonnculligan@; Colin Hill - c.hill@ucc.ie; Roy D Sleator* - roy.sleator@cit.ie * Corresponding author Published: 23 November 2009 Received: 30 October 2009 Accepted: 23 November 2009 Gut Pathogens 2009, 1:19 doi:10.1186/1757-4749-1-19 This article is available from: /content/1/1/19 © 2009 Culligan et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Gastrointestinal disease is a major cause of morbidity and mortality worldwide each year. Treatment of chronic inflammatory gastrointestinal conditions such as ulcerative colitis and Crohns disease is difficult due to the ambiguity surrounding their precise aetiology. Infectious gastrointestinal diseases, such as various types of diarrheal disease are also becoming incre