原创力文档profiling re1rest-mediated histone modifications in the human genome剖析re1rest-mediated组蛋白在人类基因组中进行修改.pdfVIP
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profiling re1rest-mediated histone modifications in the human genome剖析re1rest-mediated组蛋白在人类基因组中进行修改
Volume 10, Issue 1, Article R9Zhenget al.2009 Open Access
Research
Profiling RE1/REST-mediated histone modifications in the human
genome
*† ‡ *§
Deyou Zheng , Keji Zhao and Mark F Mehler
Addresses: *Institute for Brain Disorders and Neural Regeneration, Department of Neurology, Rose F Kennedy Center for the Study of
Intellectual and Developmental Disabilities, Albert Einstein College of Medicine, Morris Park Avenue, Bronx, NY 10461, USA. †Department of
Genetics and Neuroscience, Albert Einstein College of Medicine, Morris Park Avenue, Bronx, NY 10461, USA. ‡Laboratory of Molecular
Immunology, National Heart, Lung and Blood Institute, National Institute of Health, Rockville Pike, Bethesda, MD 20892, USA. §Departments
of Neuroscience, and Psychiatry and Behavioral Sciences, Einstein Cancer Center, Albert Einstein College of Medicine, Morris Park Avenue,
Bronx, NY 10461, USA.
Correspondence: Deyou Zheng. Email: dzheng@
Published: 27 January 2009 Received: 24 November 2008
Accepted: 27 January 2009
Genome Biology 2009, 10:R9 (doi:10.1186/gb-2009-10-1-r9)
The electronic version of this article is the complete one and can be
found online at /2009/10/1/R9
© 2009 Zheng et al.; licensee BioMed Central Ltd.
This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which
permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: The transcriptional repressor REST (RE1 silencing transcription factor, also called
NRSF for neuron-restrictive silencing factor
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