原创力文档prostaglandin e2 metabolism in rat brain role of the blood-brain interfaces前列腺素e2在老鼠大脑新陈代谢作用的血脑接口.pdfVIP
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prostaglandin e2 metabolism in rat brain role of the blood-brain interfaces前列腺素e2在老鼠大脑新陈代谢作用的血脑接口
Cerebrospinal Fluid Research BioMed Central
Research Open Access
Prostaglandin E2 metabolism in rat brain: Role of the blood-brain
interfaces
1 1 1,2
Eudeline Alix , Charlotte Schmitt , Nathalie Strazielle and Jean-
François Ghersi-Egea*1
Address: 1INSERM, U 842, Lyon; Université de Lyon; Faculté de médecine Laennec, UMR-S842, Lyon, F69372, France and 2Brain-i, 34 Rue du Dr
Bonhomme, Lyon, F69008, France
Email: Eudeline Alix - eudeline.alix@chu-lyon.fr; Charlotte Schmitt - schmitt.charlotte@;
Nathalie Strazielle - strazielle@lyon.inserm.fr; Jean-François Ghersi-Egea* - ghersi-egea@lyon.inserm.fr
* Corresponding author
Published: 4 March 2008 Received: 3 December 2007
Accepted: 4 March 2008
Cerebrospinal Fluid Research 2008, 5:5 doi:10.1186/1743-8454-5-5
This article is available from: /content/5/1/5
© 2008 Alix et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Prostaglandin E (PGE ) is involved in the regulation of synaptic activity and
2 2
plasticity, and in brain maturation. It is also an important mediator of the central response to
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