prospects of nanotechnology in clinical immunodiagnostics在临床immunodiagnostics纳米技术的前景.pdfVIP

Sensors 2010, 10, 6535-6581; doi: 10.3390/s100706535 OPEN ACCESS sensors ISSN 1424-8220 /journal/sensors Review Prospects of Nanotechnology in Clinical Immunodiagnostics Anees A. Ansari 1,*, Mansour Alhoshan 1,2, Mohamad S. Alsalhi 1,3 and Abdullah S. Aldwayyan 1,3 1 King Abdullah Institute for Nanotechnology, King Saud University, Riyadh-11451, P.O. Box-2455, Saudi Arabia; E-Mails: malsalhy@ (M.S.A.); dwayyan@ (A.S.A.) 2 Department of Chemical Engineering, College of Engineering, King Saud University, Riyadh-11451, P.O. Box-2454, Saudi Arabia, E-Mail: alhoshanm@ 3 Department of Physics and Astronomy, College of Science, King Saud University, Riyadh-11451, P.O. Box-2455, Saudi Arabia * Author to whom correspondence should be addressed; E-Mail: aneesaansari@; Tel.: +966-1-4676838; Fax: +966-1-0545797441. Received: 30 May 2010; in revised form: 12 June 2010 / Accepted: 31 June 2010 / Published: 7 July 2010 Abstract: Nanostructured materials are promising compounds that offer new opportunities as sensing platforms for the detection of biomolecules. Having micrometer-scale length and nanometer-scale diameters, nanomaterials can be manipulated with current nanofabrication methods, as well as self-assembly techniques, to fabricate nanoscale bio-sensing devices. Nanostructured materials possess extraordinary physical, mechanical, electrical, thermal and multifunctional properties. Such unique properties advocate their use as biomimetic membranes to i