psychotic mania in glucose-6-phosphate-dehydrogenase-deficient subjectsglucose-6-phosphate-dehydrogenase-deficient科目的精神病躁狂.pdfVIP
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psychotic mania in glucose-6-phosphate-dehydrogenase-deficient subjectsglucose-6-phosphate-dehydrogenase-deficient科目的精神病躁狂
Annals of General Hospital
Psychiatry BioMed Central
Primary Research Open Access
Psychotic mania in glucose-6-phosphate-dehydrogenase-deficient
subjects
Alberto Bocchetta*
Address: Bernard B. Brodie Department of Neurosciences, University of Cagliari, Italy
Email: Alberto Bocchetta* - bocchett@unica.it
* Corresponding author
Published: 13 June 2003 Received: 03 March 2003
Accepted: 13 June 2003
Annals of General Hospital Psychiatry 2003, 2:6
This article is available from: /content/2/1/6
© 2003 Bocchetta; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all
media for any purpose, provided this notice is preserved along with the articles original URL.
Abstract
Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency has been associated with
acute psychosis, catatonic schizophrenia, and bipolar disorders by previous inconclusive reports. A
particularly disproportionate rate of enzyme deficiency was found in manic schizoaffective patients
from 662 lithium patients surveyed in Sardinia. The purpose of this study was to describe clinical
characteristics which may be potentially associated with G6PD deficiency.
Methods: Characteristics of episodes, course of illness, family pattern of illness, laboratory tests,
and treatment response of 29 G6PD-deficient subjects with a Research Diagnostic Criteria
diagnosis of manic schizoaffective disorder w
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